Mind Enhancements: Exploring Psilocybin for Migraines, and Potential Anti-Cancer Properties
Weekly Shroom Droppings 🚀
🥊 | Slaying those fat cells🧬 | Mushroom warriors against cancer🧺 | Mushroom farming revolution
🤙Hey Shroomer! This week, we're diving deep into mushroom powerhouses that combat obesity, cancer, and more. Plus, a game-changer in the mushroom farming world!
HEALTH HUSTLE
🥊 Fighting fat cells 🥊 Oyster mushroom (Pleurotus ostreatus) ethanolic extract zaps those fat cells by disabling a crucial fat-making process without tampering with genetic signals.
🍨 Insulin resistance fighters 🍨 Reishi and shiitake (Lentinula edodes) offer up superhero polysaccharides and terpenoids that give insulin a boost, lowering blood sugar levels, improving metabolic health, and slashing insulin resistance markers by over 30%.
❤️🩹 Wound healing boosters ❤️🩹 A wound healing marvel has hit the scene with a novel hydrogel film incorporating lion's mane mushroom extract (Hericium erinaceus). This powerful combo of polyvinyl alcohol, chitosan, and ergosterol speeds up wound healing.
💤 Fatigue fighter 💤 Shake off that tired feeling with a mix of polysaccharides from Pleurotus eryngii, Agrocybe aegerita, and Agaricus bisporus mushrooms in a 1:2:2 ratio. This dynamic duo supercharges antioxidant levels and extends your endurance during physical activities.
🪄 Marvels unleashed 🪄 Lion's mane enhances nerve growth and brain health, pumping up nerve regeneration markers by over 50%. Agaricus blazei boosts immune response and reduces inflammation, powering up antioxidant activity by up to 60%.
CANCER CRUSHERS 🧬
🧬 Bioactives vs. cancer 🧬 Reishi (Ganoderma lucidum) and turkey tail (Trametes versicolor) compounds take out cancer cells by inducing apoptosis (cell death) and halting tumor growth. Reishi tidies up colorectal cancer cell growth, while turkey tail amps up immune cells to combat tumors.
🎯 Targeting tumor cells 🎯 Three Ganoderma species (G. resinaceum, G. australe, and G. mbrekobenum) aim and fire at liver and breast cancer cell lines, showing exceptional results. G. resinaceum exhibited extraordinary effectiveness against liver cancer cells, significantly reducing cell viability and inducing apoptosis without harming healthy cells.
🧪 Liver cancer fighters 🧪 Cantharellus cibarius, Craterellus cornucopioides, Ramaria formosa, and Hydnum repandum step up to the cancer fight, particularly against liver cancer cells (HepG2). Hydnum repandum shines the brightest, triggering apoptosis, boosting pro-apoptotic proteins, and dialing down cyclin D1 - a protein associated with cancer progression.
⚡️ Cervical cancer slayers ⚡️ Crude extracts from Omphalotus nidiformis mycelium cave in cervical cancer cells, inducing apoptosis and autophagy. Key components like 9-octadecenamide and squalene play leading roles in this destructive performance.
PSILOCYBIN & LEGISLATION
💢 Cluster headache relief 💢 Magic mushrooms can snuff out cluster headaches in patients who haven't found relief with traditional treatments. Clinical trials show a 50% reduction in attack frequency after psychedelic therapy.
🌿 Antidepressant effects 🌿 Psilocybin therapy offers up a 47% remission rate and sustained symptom reduction for up to six months, transforming cognitive flexibility, mood regulation, and default mode network activity.
🩺 Missouri psilocybin access 🩺 A fabulous new bill opens the door to psilocybin therapy for PTSD, depression, and substance use disorders, granting access to adults 21+ under medical supervision.
📈 Exposure rising 📈 Calls to U.S. poison centers for psilocybin exposure have skyrocketed by 317% over five years, with 133 reports in Colorado alone between March and December 2024. Nationwide, 12.5 million adults used psychedelics in the past year, with psilocybin topping the list at 4.9 million.
💫 Lasting changes 💫 A single dose of psychedelics rewires brain cells in the prefrontal cortex, causing enduring changes in neural connections and communication. Even after gene expression returns to normal within a month, these alterations persist.
❄️ Meet the ITW Snowball ❄️ InoculateTheWorld unveils Snowball, a groundbreaking Psilocybe cubensis strain with a cloud-like shape, rapid growth, packed fruits, and intense deep blue bruising. This extraordinary mutation from Penis Envy genetics boasts potency of up to 1.8% psilocybin.
ECOLOGY & CONSERVATION
🌱 Mushroom farming 🌱 Mushrooms, a minimal land requirement crop, yield $500-$1,000 per month from just 100 square feet, all while using recycled agricultural waste. Successful projects in Kenya, India, and Bangladesh pump up incomes and sustainability, empowering thousands of participants.
🔌 Mycelium innovation 🔌 Mushroom mycelium is transforming industries with sustainable alternatives in leather, packaging, and more. Mycelium-based materials decompose in 30 days, reducing pollution by over 50% compared to plastics.
🌽 Fertilizer emissions 🌽 Arbuscular Mycorrhizal Fungi (AMF) reduce harmful fertilizer emissions by 34.6% in black soil and 22.5% in fluvo-aquic soil, all while maintaining maize yield.
☕ Coffee growth ☕ AMF and PSF supercharge coffee seedling growth in low-phosphorus soils, offering eco-friendly alternatives to synthetic fertilizers.
🪵 Magic's roots 🪵 Australia is home to Psilocybe subaeruginosa, the genetic origin of wood-loving magic mushrooms found worldwide. This lapidary mushroom species spread via woodchips, becoming invasive in the Northern Hemisphere.
🕸️ Amazonian spider fungi 🕸️ Researchers discovered three new fungal species in the Amazon rainforest-two in the genus Marasmius and one in Pusillomyces. These fungi create intricate networks to obtain nutrients and thrive in challenging environments.
GROWING GOURMET
🔋 Vitamin D boost 🔋 Eating golden oyster mushrooms (Pleurotus citrinopileatus) turbocharges vitamin D levels.
🥣 Yogurt benefits 🥣 Polysaccharides from champignon and reishi mushrooms significantly amplify yogurt's nutritional profile. Champignon contributes about 6% carbohydrates and 6.2% proteins, while reishi offers a robust 30% carbohydrates and 12.6% proteins.
🐰 For the bunnies 🐰 Oyster mushroom extract significantly enhances growth and immune function in rabbits. When included at 10% of diet weight, it improves weight gain and feed efficiency, and reduces cholesterol and glucose levels. The extract also increases lymphocyte counts, fortifying the immune system.
🦪 Oyster growth 🦪 Pleurotus florida tops the charts in yield, fresh weight, and fruiting performance, achieving the highest fresh weight (1.13 oz). Lime treatment at 0.18-0.35 oz lime per 33 lbs substrate improves pH and substrate quality, enhancing productivity by over 40%. Perfect for commercial cultivation!
USA-GROWN, COME ON! 📣
waar·di·a [w particles]nounA phony claim that seeks to exploit consumers by promoting a product as "USA made" or "grown," while using inferior ingredients or production methods.
Buying mushroom products can be a minefield! To navigate effectively, we're diving into the "USA grown" narrative. In the coming weeks, we'll uncover tips to help you pick the best mushroom products.
Mushrooms have a long and storied history, with roots in China's 800-year-old cultivation techniques and a rich cultural history in Mesoamerica. Despite their deep roots, much of Western medicine is only now beginning to appreciate fungi as a source of healing.
While supporting local growers is impactful, "Grown in the USA" doesn't always equal quality. Many U.S. farms focus on culinary mushrooms like buttons, not medicinal varieties like reishi, and can't provide the quantities needed for functional powders. On top of that, some brands cut corners by using grain-based mycelium fillers in attempts to dilute costly mushroom components. This not only deceives consumers but also undermines centuries of traditional mushroom wisdom.
Remember: Informed health choices are key! Don't allow fear or biased marketing to keep you from exploring mushrooms' vast capabilities.
TRUSTED MUSHROOM SUPPLEMENTS 🌱
It's important to choose mushroom supplements from reliable sources. Here are some brands we trust:
- Birch Boys: For family roots, try their top-notch loose-leaf chaga tea.
- Fruiting Bodies: Their mushroom essences are innovative and promising.
- Mālama Mushrooms: This family-owned Hawai'i business crafts our favorite Lion's Mane coffee.
- Naturealm: Their research-backed mushroom powder blend, Sacred 7, is earning attention for potential epilepsy management. Shroomer readers score 25% off their first purchase with code SHROOMY at checkout.
- Real Mushrooms: Established over 40 years ago, they offer an extensive library of single-species mushroom supplements, like tremella.
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- ūü§†Nature's powerhouse in nutritional and health realm: Oyster mushroom (Pleurotus ostreatus) ethanolic extract effectively zap fat cells, enhancing metabolic health and energy levels.
- ūüôāMushrooms for better brain health: Polysaccharides from Lion's Mane mushroom (Hericium erinaceus) significantly increase nerve regeneration markers, improving cognitive function and reducing symptoms of depression.
- ūüéČLearning from the fungi kingdom: Fungal education and self-development can unlock valuable insights for protagonists in personal growth, as well as deepen understanding of nature's fantastic marvels.
- ūüéČSustainability in farming: Cultivating mushrooms using minimal land requirement and recycled agricultural waste unlocks numerous benefits, boosting income, improving sustainability, and conserving resources for a better planet.
- ūüźĻMushrooms for wellness goals: Incorporating tremella and other mushrooms into yogurt significantly enhances its nutritional profile, offering advantages for mental and physical health.
- ūüí°Microdosing psychedelics for overall health: Integrating microdoses of psilocybin into daily life can help improve focus, boost creativity, and enhance overall well-being, alongside potential benefits for mental health conditions.
